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Cambridge Electronic Design programmable acquisition and analysis software spike2
Programmable Acquisition And Analysis Software Spike2, supplied by Cambridge Electronic Design, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/programmable+acquisition+and+analysis+software+spike2/spike2+software/pm40506586-58-19-22
Average 90 stars, based on 1 article reviews
programmable acquisition and analysis software spike2 - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Reducing lung liquid volume in fetal lambs decreases ventricular constraint.
Article Snippet: BACKGROUND: This study evaluated whether an increased left ventricular (LV) pump function accompanying reduction of lung liquid volume in fetal lambs was related to increased LV preload, augmented LV contractility, or both.. METHODS: Eleven anesthetized preterm fetal lambs (gestation 128 ± 2 days) were instrumented with (1) an LV micromanometerconductance catheter to obtain LV end-diastolic volume (EDV) and end-diastolic pressure (EDP), the maximal rate of rise of LV pressure (dP/dtmax), LV output, LV stroke work, and LV end-systolic elastance (Ees), a relatively load-independent measure of contractility; (2) an endotracheal tube to measure mean tracheal pressure and to reduce lung liquid volume.. LV transmural pressure was calculated as LV EDP minus tracheal pressure.

Article Title: Major contribution of central pulmonary reservoir discharge to increased pulmonary arterial diastolic blood flow after birth in near-term lambs.
Article Snippet: .. Catheter and flow probe signals were digitized at a sampling rate of 1 kHz using programmable acquisition and analysis software (Spike2, Cambridge Electronic Design, Cambridge, UK). ..

Article Title: Greater sympathoadrenal activation with longer preventilation intervals after immediate cord clamping increases hemodynamic lability at birth in preterm lambs.
Article Snippet: 29 This study tested the hypothesis that varying degrees of hemodynamic fluctuations seen 30 after birth following immediate cord clamping were related to development of asphyxia with 31 longer cord clamp-to-ventilation intervals, resulting in higher perinatal circulating levels of 32 the catecholamines norepinephrine (NE) and epinephrine (Epi), and thus increased heart rate, 33 blood pressures and cardiac contractility after birth.. Anesthetized preterm fetal lambs were 34 instrumented with 1) aortic (AoT) and pulmonary trunk (PT) micromanometers to obtain 35 pressures and the maximal rate of pressure rise (dP/dtmax) as a surrogate measure of 36 ventricular contractility, and 2) an AoT catheter to obtain samples for blood gas and 37 catecholamine analyses.. After delivery, immediate cord clamping was followed by ventilation 38 ∼40sec (n=7), ∼60sec (n=8), ∼90sec (n=9) or ∼120sec later (n=8), with frequent blood 39 sampling performed before and after ventilation.

Article Title: Pulmonary perfusion with dynamic PEEP recruitment or sustained inflation at birth in preterm lambs.
Article Snippet: .. Catheter, micromanometer and flow probe signals were digitized at a sampling rate of 1 kHz using programmable acquisition and analysis software (Spike2, Cambridge Electronic Design, Cambridge, UK). ..

Article Title: Blunted sympathoadrenal activation accompanies hemodynamic stability after early ventilation and delayed cord clamping at birth in preterm lambs.
Article Snippet: BACKGROUND: As surges in circulating norepinephrine and epinephrine have chronotropic, pressor, and inotropic effects, we tested the hypothesis that blunted rises in these catecholamines during preterm birth accompanied hemodynamic stability observed after early ventilation and delayed cord clamping (DCC), with findings compared to immediate cord clamping (ICC) and a non-asphyxial cord clamp-to-ventilation interval.. METHODS: Anesthetized preterm fetal lambs were instrumented with arterial micromanometers to obtain pressure and the maximal rate of pressure rise (dP/dtmax) as a surrogate of ventricular contractility and an aortic catheter to obtain blood samples for catecholamine assay.. Fetuses were delivered and mechanically ventilated before cord clamping ∼1.5 min later (DCC, n= 9) or subjected to ICC with ventilation started ∼40 s later (n= 8).

Article Title: Reducing lung liquid volume increases biventricular outputs and systemic arterial blood flows despite decreased cardiac filling pressures in fetal lambs.
Article Snippet: .. Signals from catheters, 130 micromanometers and flow probes were digitized at a sampling rate of 1 kHz and displayed 131 using programmable acquisition and analysis software (Spike2, Cambridge Electronic Design, 132 Cambridge, UK). ..

Article Title: Antenatal betamethasone redistributes central blood flows and preferentially augments right ventricular output and pump function in preterm fetal lambs.
Article Snippet: The glucocorticosteroid betamethasone, which is routinely administered prior to anticipated preterm birth to enhance maturation of the lungs and the cardiovascular system, has diverse fetal regional blood flow effects ranging from increased pulmonary flow to decreased cerebral flow.. The aim of this study was to test the hypothesis that these diverse effects reflect alterations in major central flow patterns that are associated with complementary shifts in left ventricular (LV) and right ventricular (RV) pumping performance.. Studies were performed in anesthetized preterm fetal lambs (gestation = 127± 1days, term= 147days) with (n = 14) or without (n = 12) preceding betamethasone treatment via maternal intramuscular injection.

Article Title: Extended period of ventilation before delayed cord clamping augments left‐to‐right shunting and decreases systemic perfusion at birth in preterm lambs
Article Snippet: .. Signals from fluid-filled and micromanometer catheters and from flow probes were digitized at a sampling rate of 1 kHz and displayed using programmable acquisition and analysis software (Spike2, Cambridge Electronic Design, Cambridge, UK). ..

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Article Title: Reducing lung liquid volume in fetal lambs decreases ventricular constraint.
Article Snippet: BACKGROUND: This study evaluated whether an increased left ventricular (LV) pump function accompanying reduction of lung liquid volume in fetal lambs was related to increased LV preload, augmented LV contractility, or both.. METHODS: Eleven anesthetized preterm fetal lambs (gestation 128 ± 2 days) were instrumented with (1) an LV micromanometerconductance catheter to obtain LV end-diastolic volume (EDV) and end-diastolic pressure (EDP), the maximal rate of rise of LV pressure (dP/dtmax), LV output, LV stroke work, and LV end-systolic elastance (Ees), a relatively load-independent measure of contractility; (2) an endotracheal tube to measure mean tracheal pressure and to reduce lung liquid volume.. LV transmural pressure was calculated as LV EDP minus tracheal pressure.

Article Title: Major contribution of central pulmonary reservoir discharge to increased pulmonary arterial diastolic blood flow after birth in near-term lambs.
Article Snippet: .. Catheter and flow probe signals were digitized at a sampling rate of 1 kHz using programmable acquisition and analysis software (Spike2, Cambridge Electronic Design, Cambridge, UK). ..

Article Title: Greater sympathoadrenal activation with longer preventilation intervals after immediate cord clamping increases hemodynamic lability at birth in preterm lambs.
Article Snippet: 29 This study tested the hypothesis that varying degrees of hemodynamic fluctuations seen 30 after birth following immediate cord clamping were related to development of asphyxia with 31 longer cord clamp-to-ventilation intervals, resulting in higher perinatal circulating levels of 32 the catecholamines norepinephrine (NE) and epinephrine (Epi), and thus increased heart rate, 33 blood pressures and cardiac contractility after birth.. Anesthetized preterm fetal lambs were 34 instrumented with 1) aortic (AoT) and pulmonary trunk (PT) micromanometers to obtain 35 pressures and the maximal rate of pressure rise (dP/dtmax) as a surrogate measure of 36 ventricular contractility, and 2) an AoT catheter to obtain samples for blood gas and 37 catecholamine analyses.. After delivery, immediate cord clamping was followed by ventilation 38 ∼40sec (n=7), ∼60sec (n=8), ∼90sec (n=9) or ∼120sec later (n=8), with frequent blood 39 sampling performed before and after ventilation.

Article Title: Pulmonary perfusion with dynamic PEEP recruitment or sustained inflation at birth in preterm lambs.
Article Snippet: .. Catheter, micromanometer and flow probe signals were digitized at a sampling rate of 1 kHz using programmable acquisition and analysis software (Spike2, Cambridge Electronic Design, Cambridge, UK). ..

Article Title: Blunted sympathoadrenal activation accompanies hemodynamic stability after early ventilation and delayed cord clamping at birth in preterm lambs.
Article Snippet: BACKGROUND: As surges in circulating norepinephrine and epinephrine have chronotropic, pressor, and inotropic effects, we tested the hypothesis that blunted rises in these catecholamines during preterm birth accompanied hemodynamic stability observed after early ventilation and delayed cord clamping (DCC), with findings compared to immediate cord clamping (ICC) and a non-asphyxial cord clamp-to-ventilation interval.. METHODS: Anesthetized preterm fetal lambs were instrumented with arterial micromanometers to obtain pressure and the maximal rate of pressure rise (dP/dtmax) as a surrogate of ventricular contractility and an aortic catheter to obtain blood samples for catecholamine assay.. Fetuses were delivered and mechanically ventilated before cord clamping ∼1.5 min later (DCC, n= 9) or subjected to ICC with ventilation started ∼40 s later (n= 8).

Article Title: Reducing lung liquid volume increases biventricular outputs and systemic arterial blood flows despite decreased cardiac filling pressures in fetal lambs.
Article Snippet: .. Signals from catheters, 130 micromanometers and flow probes were digitized at a sampling rate of 1 kHz and displayed 131 using programmable acquisition and analysis software (Spike2, Cambridge Electronic Design, 132 Cambridge, UK). ..

Article Title: Antenatal betamethasone redistributes central blood flows and preferentially augments right ventricular output and pump function in preterm fetal lambs.
Article Snippet: The glucocorticosteroid betamethasone, which is routinely administered prior to anticipated preterm birth to enhance maturation of the lungs and the cardiovascular system, has diverse fetal regional blood flow effects ranging from increased pulmonary flow to decreased cerebral flow.. The aim of this study was to test the hypothesis that these diverse effects reflect alterations in major central flow patterns that are associated with complementary shifts in left ventricular (LV) and right ventricular (RV) pumping performance.. Studies were performed in anesthetized preterm fetal lambs (gestation = 127± 1days, term= 147days) with (n = 14) or without (n = 12) preceding betamethasone treatment via maternal intramuscular injection.

Article Title: Extended period of ventilation before delayed cord clamping augments left‐to‐right shunting and decreases systemic perfusion at birth in preterm lambs
Article Snippet: .. Signals from fluid-filled and micromanometer catheters and from flow probes were digitized at a sampling rate of 1 kHz and displayed using programmable acquisition and analysis software (Spike2, Cambridge Electronic Design, Cambridge, UK). ..



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Cambridge Electronic Design programmable acquisition and analysis software spike2
Programmable Acquisition And Analysis Software Spike2, supplied by Cambridge Electronic Design, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/programmable+acquisition+and+analysis+software+spike2/spike2+software/pm40506586-58-19-22
Average 90 stars, based on 1 article reviews
programmable acquisition and analysis software spike2 - by Bioz Stars, 2026-10
90/100 stars
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